To be fair, much of that is by design. DTF St. Louis wants to keep viewers in the dark about its central investigation throughout its run. Unfortunately, that means dragging the mystery out, especially when it comes down to Homer and Plumb's investigation.
In 1874, Fanny Angelina married physician and bacteriologist Walther Hesse, an investigator of air quality and, specifically, air-borne microbes. In the Winter of 1880-81, Hesse became a research student with Koch in Berlin and experienced firsthand the difficulty of growing microbes on gelatine and the other growth media used at the time.
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EPA found only 27 of 219 plants needed upgrades; 71 later got exemptions as Donald Trump scrapped mercury limits
And now, look at him go!